| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_9c4bd586165e78fb5d16588846952649
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_fa5d97928d5c303b11f7bb2aeb6377ad
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_06997b16adea71b043f095581dde7e97 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-36
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-80
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y305-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-14
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-24
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P19-04 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-78 |
| filingDate |
2011-06-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e3e79b3b99d20d66b8d34c364964bc89
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7f52c15ddd05a8441174e12c57615507 |
| publicationDate |
2013-04-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-2013085187-A1 |
| titleOfInvention |
Deacetylation hydrolase of hyaluronic acid, hyaluronic acid deacetylated by same and derivative thereof |
| abstract |
The present disclosure relates to a deacetylation hydrolase of a hyaluronic acid a hyaluronic acid deacetylated by same and a derivative thereof. The deacetylated hyaluronic acid and the derivative thereof have the following characteristic: a delayed initial decomposition rate on a living body; minimized decrease of molecular weight and viscosity; accelerated gelation due to a lower gelation temperature than the gelation temperature for a non-deacetylated hyaluronic acid; and an hMSC survival rate that is hardly affected by increased concentration of the deacetylated hyaluronic acid and the derivative thereof in a culture medium. As a result, the deacetylated hyaluronic acid and the derivative thereof can be useful as a bioingredient such a delivery system for a cell, gene, drug, and the like, or a support for tissue engineering, etc. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11780970-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11530301-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11730691-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11643509-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11708461-B2 |
| priorityDate |
2010-06-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |