| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_61002c3bd45dd4909d4ad35af4637461
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_b630bc58a088ee0364437a1d84696155
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_c98b1513e8f9e30e2ec40a27e62a0240
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_c648f1f5c4e78e346f7402adbbc57568
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d986b2b5b7af879063b473243076d571 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-4738 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P21-00 |
| filingDate |
2011-09-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d35fb2d79ea751ca3b08eae10abaf24d
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_25fd33108a6670556f6ddbe912fc9ecd
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_030ad67be4134ae5e4720e5e9a705ccf |
| publicationDate |
2013-03-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-2013072657-A1 |
| titleOfInvention |
CELL GROWTH INHIBITOR DERIVED FROM p16INK4a AND METHOD OF SYNTHESIZING THE SAME |
| abstract |
The various embodiments herein provide a cell growth inhibitor derived from p16 INK4a gene comprising a C-terminal segment of the p16 INK4a gene, two ankyrin repeats i.e. ankyrin III and ankyrin IV of the p16 INK4a gene, two loops i.e. loop 2 and loop 3 of the p16 INK4a gene and residues along with the loop 2 consisting Phe 90 , Glu 88 , Gly 89 , Asp 92 and Asp 84 residues. The cell growth inhibitor is a truncated form of the p16 INK4a gene and encompasses 66-156 amino acids of a full length p16 INK4a gene. The cell growth inhibitor has 42% growth inhibition at 24 hrs. The embodiments herein also provide a method of synthesizing the cell growth inhibitor using a polymer chain reaction method. |
| priorityDate |
2011-09-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |