Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_f608a06161ec96eaa00dbf03e27549a3 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_0c18fe5e5a0507e09d1517eeb3570f93 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_b81c3ecc9a3bd192c754216816991d8a http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_4267d115faa04f4205f6d5fefcca1253 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ee779bbf584bb33a648616d164850e10 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P7-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-2257 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-27 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P9-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-36 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P7-02 |
filingDate |
2011-02-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cb639d08692b9f7babb2e7586a9b0ab2 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9e434643f142ed28427692bb9d4de4d7 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_782064a75f307be19d2cc5519ba07768 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4dca7c73c0af64ac0a1ca9942f657ce6 |
publicationDate |
2013-02-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-2013035289-A1 |
titleOfInvention |
Pharmaceutical composition for treatment of thrombosis-related diseases comprising a fragment of prolactin (prl)-growth hormone (gh)-placental lactogen (pl)-family protein |
abstract |
The present disclosure relates to a pharmaceutical composition for use in the preventive and/or therapeutic treatment of thrombosis-related diseases or conditions relating to high level of plasminogen activator inhibitor 1 (PAI-1) expression, which composition comprises: A) a fragment of a polypeptide or protein of prolactin (PRL)-growth hormone (GH)-placental lactogen (PL)-family and homologous derivatives thereof, which fragment comprises from 6 to 14 consecutive amino acid residues of the amino acid sequence having general formula (I); or B) a peptide or a recombinant protein comprising said peptide, wherein the peptide is from 6 to 50 amino acids in length and has the activity to inhibit PAI-1, said peptide comprising from 6 to 14 consecutive amino acid residues of the amino acid sequence of general formula (I); or C) a polynucleotide encoding said fragment of a polypeptide or protein of A) or said peptide or recombinant protein of B). |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2017042278-A1 |
priorityDate |
2010-02-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |