Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_32f57a53515b98afbb284cb39a2f17f7 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_204587e95ece0e90f9fb0e087631b5bb http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_4c4e63f623fe2815729b056ce2157aa5 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_defe1499d58ba925c74acef0de979b22 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02A50-30 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P33-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P33-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P33-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P33-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-4985 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07B59-002 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D471-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-4184 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P33-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P33-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P33-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P33-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D471-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4985 |
filingDate |
2012-03-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c741a87176a102887da7f42aa2395059 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_34f1c55b940a60301c15c0bb2e37e5e7 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_12a360b20745913b9d503048eb8b5d44 |
publicationDate |
2013-01-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-2013029997-A1 |
titleOfInvention |
Pyrazinoisoquinoline compounds |
abstract |
This invention in one embodiment is directed to a compound of Formula Ia; n n n n n n n n n n where the designation (R) indicates that the designated carbon has the (R) stereochemistry; and wherein Z 1 is hydrogen or fluorine; Z 2 is hydrogen, deuterium, or fluorine; Z 3 is deuterium; Z 4 is fluorine; m is an integer from 0 to 10; n is an integer from 0 to 2; provided that: the sum of m+n does not exceed 10; and when both Z 1 and Z 2 are hydrogen, the sum of m+n is greater than 0, and pharmaceutically acceptable salts thereof. This invention also provides compositions comprising one or more compounds of this invention and a carrier and the use of the disclosed compounds and compositions in methods of treating diseases and conditions that are beneficially treated by administering an antihelminthic agent, such as praziquantel. |
priorityDate |
2011-03-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |