Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_fe988622c59fde99bff610d9b73ce160 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_bcbb2ffd73a81539133323c6726c616f http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d4260a256b5f28ea7d92b4c1f5b921d0 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_87c25bde9be54ab8839fd56a9a365ef2 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_3857faf8eb449616e2d2edb353828850 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-0008 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P19-36 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-63 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-53 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N1-21 |
filingDate |
2009-10-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e210af07fce211ece701d7414eb4e1dd http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5f5687bdd75b8118132d4022ba0d849c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d775c180d39ae688011768dfc06dd268 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8b445042d831975f3d18ca2cb4cc3bc9 |
publicationDate |
2013-01-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-2013029378-A1 |
titleOfInvention |
Novel enzyme |
abstract |
The invention provides an isolated formate dehydrogenase (FDH) polypeptide specific for NADP + and an isolated FDH polypeptide having an adenine ribose recognition loop comprising a first large amino acid and a second amino acid, wherein the first and second amino acid are arranged in space to allow the second amino acid to bond with a phosphate group. Also provided is a variant of an BAD + specific FDH polypeptide, wherein the adenine ribose recognition loop has been mutated at least one position to alter the three dimensional polypeptide structure of the adenine ribose recognition loop to allow a phosphate group to be recognised. The polypeptides of the invention can be used in the conversion of NADP + to NADP or in the conversion of BAD + to NASH. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2013203137-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8795991-B2 |
priorityDate |
2008-10-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |