Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_b17177477b351b6973f8ad48d994165a http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_562e4af016953c0a80e09960559ed0d2 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_c49cd0a7cdf4fd132d81f27ecd44f70e |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-81 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-4711 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N1-19 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-02 |
filingDate |
2011-01-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7f9d8d93e9d22c348ec9880ff2568790 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4cd92a2f08e7667719f1d8ef9f2a9157 |
publicationDate |
2013-01-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-2013022988-A1 |
titleOfInvention |
Yeast cells expressing amyloid beta and uses therefor |
abstract |
Disclosed are yeast cells expressing a polypeptide comprising a signal sequence and a human amyloid beta protein. Also disclosed are methods of screening yeast cells to identify compounds that prevent or suppress amyloid beta-induced toxicity and genetic suppressors or enhancers of amyloid beta-induced toxicity. Compounds identified by such screens can be used to treat or prevent neurodegenerative disorders such as Alzheimer's disease. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2016513475-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10240160-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11047848-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11261453-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-3842514-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2020103289-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-3736343-A1 |
priorityDate |
2010-01-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |