Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_c0caff3bf0deb84e360d07cc5e12bbb3 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_abce2697843a07a6d83bfe754c3d0fec |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2800-52 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2710-16632 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K35-763 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-57484 |
classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-00 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K35-763 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K35-76 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 |
filingDate |
2011-11-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9189746f7f22e08a86ed3d93ee103b1b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f9f84444c8c1a6e67bc7e98f8ab424a4 |
publicationDate |
2012-11-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-2012301506-A1 |
titleOfInvention |
Oncolytic Virus as an Inducer for Innate Antitumor Immunity |
abstract |
The present invention is directed to the administration of FusOn-H2, an HSV derived oncolytic virus, to treat tumor cells that are resistant to the lytic effect of the virus. Administration of FusOn-H2 induces the patient's innate immune responses to tumor cells via neutrophils, which are able to destroy tumors efficiently when they migrate to the tumor mass. With the induced innate antitumor immunity, FusOn-H2 is effective at eradicating tumors even when it is used at very low doses. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2009215147-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8986672-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2015246086-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2022173767-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2023178191-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10039796-B2 |
priorityDate |
2010-11-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |