Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_18d92c46f60af8af24e262b67381d7eb http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_72b9e8769d05872ab0d38da6c7a6ddeb |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2500-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2800-108 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2799-027 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2501-608 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2501-606 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2501-603 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2501-604 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2501-602 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2501-999 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2510-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2502-11 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-85 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K35-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-5073 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-0696 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-85 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K35-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-02 |
filingDate |
2010-09-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6048ca7dd459ec6879ae48300a9316e5 |
publicationDate |
2012-11-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-2012301438-A1 |
titleOfInvention |
Reprogramming Blood Cells to Pluripotent and Multipotent Stem Cells |
abstract |
The present invention is based on the seminal discovery that cord blood (CB) and adult bone marrow (BM) CD34+ cells can be reprogrammed to early stem cells. The invention provides the reprogramming of CB and adult bone marrow (BM) CD34+ cells from subjects without any pre-treatment. Provided are methods for reprogramming blood cells of a subject. Also provided are methods of disease modeling and methods of generating subject-specific differentiated cells. In addition, the invention provides methods of identifying an agent that alters a function of subject-specific differentiated cells as well as isolated pluripotent or multipotent stem cells reprogrammed from blood cells. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-3902909-A4 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2017327796-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9540612-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2015160982-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2016097036-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2020080057-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10443044-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-105705021-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2999343-A4 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2016160858-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2019165320-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11261429-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9677085-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-111019894-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2013116307-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-112204149-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2014153346-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10435710-B2 |
priorityDate |
2009-09-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |