http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2012296099-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_11bc6f8201e9a1521143729ac8693469 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_53653b69e30171e9bcf707ed88eed1ba http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2ee472d474bdfae558bf946db720cb2f |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D309-30 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D309-30 |
| filingDate | 2010-11-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cef0164fa37e8d86cfd09dbe5b6a5615 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_179dca0201d0211742fbc97ee7f803f8 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_280e95f766a1f40b0ff42b7d67b4618f |
| publicationDate | 2012-11-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | US-2012296099-A1 |
| titleOfInvention | Methods for preparing statin compounds by lactonization |
| abstract | A method for preparing a statin compound by lactonization is disclosed, which comprises the following step: lactonizing a compound of formula II into the compound of formula I in the presence of a strong acid catalyst and a dehydrant in a first solvent, n n n n n n n n n n n n wherein Z represents H, ammonium, or a metal cations; n R 1 is H or C 1 -C 6 alkyl, preferably H or CH 3 , n R 2 is CH 3 , OH, CH 2 OH, CH 2 OC(O)R 3 , CH 2 OR 3 , or COOR 4 , preferably CH 3 or OH, n R 3 and R 4 are independently selected from the group consisting of H and C 1 -C 6 alkyl. |
| priorityDate | 2009-11-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 164.