| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_96953b0daeec6c9b29443772ef895ba8
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_05b86724c76c7643b6209f39bf55318e
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_0d0446a5bd77c7da68216fc2e3f05d48
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_81c150af8961fd5ae4f74c3565019f3d
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_f3cae988ce5dda085418ce1b385f5d0a
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_66467fe5b0acf469afb972f300bcfb87
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d7e83c6e2e96fcef163216307a2b0865
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_b8c462cd6ddcab74fe6a59c89044cabb |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G16B20-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G06F17-11
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G16B5-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G16B20-20 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G16B20-20
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G16B5-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G16B45-00 |
| filingDate |
2012-03-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f1fcf066828324be587b323d7e2b7458
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0cb94a631a28c8ed33d16c9147f82879
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c73208c2af5d0b1e4c3d7fb1a850979e
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ca6bdc1ae1c0e576ba2a36a57290893a
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c38879d0d0837776eff4dd458ddbb146 |
| publicationDate |
2012-11-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-2012283956-A1 |
| titleOfInvention |
Method and system for predicting selective cancer drug targets |
| abstract |
A method for creating a metabolic map of metabolic reactions by selecting metabolic reactions active in cancer cells. A core set of metabolic reactions occurring in the cancer cells is designated. For each permutation, whether inhibition of the k-th non-core reaction together with inhibition of all previously deleted non-core reactions results in inhibition of any of the core reactions or results in inhibition of the flux of biomass metabolites to biomass is determined. If inhibition of the k-th non-core reaction and inhibition of all previously deleted non-core reactions does not result in inhibition of any core reactions and does not result in inhibition of the flux of biomass metabolites to biomass, then the k-th non-core reaction is deleted from the set of non-core reactions. The number of permutations for which the k-th non-core reaction is not deleted is determined and a metabolic map is then created based on that number. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11768595-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-108427862-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11500528-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-105138862-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2012330560-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-105138862-B
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2016148115-A1 |
| priorityDate |
2011-03-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |