http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2012282633-A1
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_27aa238e8bdb77c1a542cdc048793ff5 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_58d3f72b2d7a645913c72292da3dbc65 |
classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-71 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-2863 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-573 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-574 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-40 |
filingDate | 2011-01-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_99b48be7ecd4a08427ed21f8d19c3050 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_69d492d76d1b410bf1ca4e1488eb805e |
publicationDate | 2012-11-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | US-2012282633-A1 |
titleOfInvention | Antibody specific to activated egfr |
abstract | Disclosed is a means for accurately measuring activated EGFR regardless of whether phosphorylation has occurred or not. The antibody or antigen-binding fragment thereof according to the present invention can bind to activated EGFR regardless of whether the activated EGFR is in a phosphorylated form or in a nonphosphorylated form. By carrying out an immunoassay using the antibody or antigen-binding fragment thereof, activated EGFR in a sample can be measured more accurately than by conventional methods. Abnormal activation of EGFR is responsible for the onset of cancer, and is regarded as a therapeutic target. Therefore, the antibody or antigen-binding fragment thereof according to the present invention is also useful for detection of cancers, in particular, cancers to which a molecular target drug(s) whose target is EGFR is(are) to be administered. |
isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2014028221-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2879712-A1 |
priorityDate | 2010-01-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 80.