Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_bf4d06134f2ef31cb87df8cb4e9cd428 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_e40d73555b988e4cb5b6af42895d8aab http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_555896a2f43ea629dbc0f99b94cfd297 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2800-56 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2800-52 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-5748 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-57426 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-574 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-5011 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-02 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C40B30-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-574 |
filingDate |
2012-01-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_749f5a9f262cdf94b2275467e6adde84 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f9e660a36d850d60086d206506b81046 |
publicationDate |
2012-11-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-2012277109-A1 |
titleOfInvention |
Proximity-mediated assays for detecting oncogenic fusion proteins |
abstract |
The present invention provides antibody-based arrays for detecting the activation state and/or total amount of one or a plurality of oncogenic fusion proteins in a biological sample such as whole blood or tumor tissue and methods of use thereof. In certain instances, the activation state and/or total amount of oncogenic fusion protein(s) present in a sample can be measured in combination with one or a plurality of signal transduction molecules. The compositions and methods of the present invention have the advantages of specificity associated with enzyme-linked immunosorbent assays, sensitivity associated with signal amplification, and high-throughput multiplexing associated with microarrays. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10557851-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10466244-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-110914690-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11787844-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2014122582-A1 |
priorityDate |
2009-10-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |