Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_688c4c706aee585cb949573249901253 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d90e64f2e165445e9f5baa82b565c761 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_3a89a2b217e5d2ca07146f143d22f9b5 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_932c7d0e1aeeb4d4dfccf74670a62ed4 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_e96f596a63cf3e01c1c45af5fd5352ec http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_cfc3d4443186983ab6c691f38133b926 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_0d916805efa9146b32c6e326bce892d9 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-543 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-5254 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2760-16134 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2760-16122 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2760-16162 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-145 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-005 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N7-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-12 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-54 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N7-04 |
filingDate |
2010-10-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8ae9806c6d17d7dcf8b85607a324dca6 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8bf4a44174b42a549465a2488faa2f3e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6eba03d9b08a7db573db41742111d474 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_04a94c82bc61cca861761091d89a88d2 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_82f09ece9efcd4483145d576455da83f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_07f8ffe474ee7d4f588b5e248b8786ea http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_96b7566667287ec131c6f1cf14a23cd3 |
publicationDate |
2012-10-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-2012269849-A1 |
titleOfInvention |
Attenuated influenza viruses and vaccines |
abstract |
The present provides attenuated influenza viruses comprising a modified viral genome containing a plurality of nucleotide substitutions. The nucleotide substitutions result in the rearrangement of preexisting codons of one or more protein encoding sequences and changes in codon pair bias. Substitutions of non-synonymous and synonymous codons may also be included. The attenuated influenza viruses enable production of improved vaccines and are used to elicit protective immune responses. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10548967-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11028408-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11549101-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-109563492-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2020502080-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2018147276-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10793834-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-110225765-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2014145290-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10316294-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2018102586-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2014161771-A1 |
priorityDate |
2009-10-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |