| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_c7fb2db7b470d4cf37be4701a704d526
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_746a9a535038387c55b81ea5727bddfb
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_9ffbd252f7378c8770d7819b808c4d23
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_51275226fb2d4dd08c28252984b9dbcc
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_5fadc18369dac6778fe6217aed49ada7 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-00 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-6432
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-435
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y304-21006
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-60
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P39-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-4826
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-4833
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-4846
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-4853
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P7-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P7-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P7-04 |
| classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-00 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-64
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-96
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-57
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K48-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-48
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P7-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P39-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N1-19
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N1-21 |
| filingDate |
2012-03-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_de6577823464a90d37d134bdbee0c402
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3d291b6d9d963e901e6147269141a032
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_114485ce503cce8c4daf7938af06d01f
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_94966f728a9fa478a5ebd7b32259bad2 |
| publicationDate |
2012-10-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-2012269788-A1 |
| titleOfInvention |
Antidotes for factor xa inhibitors and methods of using the same |
| abstract |
The present invention relates antidotes to anticoagulants targeting factor Xa. The antidotes are factor Xa protein derivatives that bind to the factor Xa inhibitors thereby substantially neutralizing them but do not assemble into the prothrombinase complex. The derivatives describe herein lack or have reduced intrinsic coagulant activity. Disclosed herein are methods of stopping or preventing bleeding in a patient that is currently undergoing anticoagulant therapy with a factor Xa inhibitor. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11168147-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10588950-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10335375-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10647780-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9849125-B1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10675335-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8889129-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9388401-B2 |
| priorityDate |
2007-09-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |