http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2012267522-A1

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filingDate 2012-04-30-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f1296260e9d97d543e15a03678e5aa9f
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publicationDate 2012-10-25-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber US-2012267522-A1
titleOfInvention Method and apparatus for identifying proteins in mixtures
abstract Protein identification in a complex sample begins by selecting a database having proteins likely to be in the sample. In-silico digestion is performed and a target peptide is selected from produced peptides. The masses of the Y- and B-ion fragments of the target peptide are determined. These masses are used to search previously obtained low- and high-energy AMRTs obtained from LC/MS analysis of the complex sample for masses on the list. Any mass observed in the data within a detection threshold are considered a hit. If enough hits accumulate in a given retention time, the target peptide is identified as being in the sample. The list of peptides identified in the complex sample can be used to identify the proteins present in the sample, track the chromatographic retention times of peptides between samples, and quantitate the peptides and proteins present in complex samples.
isCitedBy http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2013228677-A1
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Total number of triples: 33.