Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_7de2791dd613ba76a789c76d139d974f http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_9be66c99a730caefe7af8052403be765 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_e4eb08f3902c26ad9e1d2f0eaf310862 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_b72074f5eae6e964d7d4fdb80860dc4e http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ab076dbaa11ba7c868d14dcc15765a6a http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_b7f40a9678f4696444fcd0ebf616f05e |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-216 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-0024 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-146 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4418 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-00 |
filingDate |
2010-10-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c4685696d5fa283b11782359f15fabc3 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5ae4feda857b5413b8aededc56fba51f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f261c9b607c6a2df683c133d0f088188 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bb6b90c13bfc797eee76f9ee581b5a96 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5c46924425bab8f48b2b955de2e23c6e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3158a0643bbbf192ad84db405f8b0216 |
publicationDate |
2012-10-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-2012252851-A1 |
titleOfInvention |
Delivery system for sustained release of a calcium-channel blocking agent |
abstract |
A delivery system for sustained release of a calcium-channel blocking agent is adapted for introduction in the cerebrospinal fluid of a subject. The delivery system comprises a solid dispersion product of a calcium-channel blocking agent in a mixture of a (i) first poly(lactide-co-glycolide) having a molecular weight distribution centered around a first number average molecular weight Mn 1 and a (ii) second poly(lactide-co-glycolide) having a molecular weight distribution centered around a second number average molecular weight Mn 2 , wherein Mn 1 is in the range of from 2000 to 3000 g/mol and the ratio of Mn 1 /Mn 2 is from 1.8 to 3.5. The delivery system is deposited in the vicinity of or adjacent to a blood vessel showing vasospasm or suspected of developing vasospasm. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-113384551-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-111405894-A |
priorityDate |
2009-10-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |