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filingDate 2011-09-20-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7604f6bb24db1af86cc1dbe809436ba7
publicationDate 2012-10-04-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber US-2012252098-A1
titleOfInvention Dissociation of Product-complexed Contaminants in Chromatography
abstract The invention provides methods and materials for using apatite chromatography supports to dissociate and remove contaminants that are complexed to biological products. The invention further provides materials and methods for dissociating aggregations of target biological molecules or improperly folded target molecules to improve purification of the target molecule.
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