abstract |
Provided are a triterpene derivative represented by a general formula (I), a pharmaceutically acceptable salt thereof, and an agent for preventing or treating chronic hepatitis C comprising the triterpene derivative or the salt as an active ingredient: n n n n n n n n n n [in the formula (I), R 1 represents a carboxyl group, a hydroxymethyl group, —CH 2 OSO 3 H, or n n n n n n n n n n and R 2 represents —OR 3 or —O— (CH 2 ) m-OR 4 , where R 3 represents a benzyl group which may be substituted with a hydroxymethyl group, a dimethylaminomethyl group, a phenylaminomethyl group, a morpholinomethyl group, a carboxyl group, or a formyl group, a C 1-6 alkyl group, a C 2-6 alkenyl group, a C 2-6 alkynyl group, or a hydroxy C 1-6 alkyl group, R 4 represents a phenyl group which may be substituted with a carboxyl group, and m represents an integer of 1 to 3, with the proviso that a case where R 1 is —CH 2 OH, and R 3 is a C 1-6 alkyl group, a C 2-6 alkenyl group, or a benzyl group is excluded]. |