| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_4fe050f573526b29d0971ca7ab0d44f3
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_3db65e9f438bf97e59196f4bc6559020
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_9ae1c74e99097aaf7ea6f545c242e090
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_947ca3f6659508f76be1fb64b9c903b8 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-177
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-70539
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K19-00 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K19-00 |
| filingDate |
2012-03-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4e077f115300c64114cb6da5f5260427
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bf6230e2fb432c2d2e2dcc1f197a0bbf
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_09b8929b70f93a2afd33bdd146527cb3
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_73fa3dc3046d228629b04fd90c227743 |
| publicationDate |
2012-09-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-2012245332-A1 |
| titleOfInvention |
Mhc oligomers, components thereof, and methods of making the same |
| abstract |
The present invention relates to an MHC binding polymer suitable for the oligomerisation of individual MHC monomers. The MHC binding polymer comprises a first segment and a second segment, wherein the first segment comprises a peptide capable of binding in a binding groove of an MHC molecule, and wherein the second segment comprises a linking segment and a recognition site for coupling the MHC binding polymer with a specific partner. The linking segment is a polymer with a length of at least 10 Angstrom in its native conformation. Further it relates to an MHC oligomer containing such MHC binding polymers. Individual functional MHC complex monomers are oligomerised via their peptides bound in the peptide binding groove of the complex. Moreover, it relates to a method of making such MHC binding polymer and oligomer and various methods using the same. |
| priorityDate |
2006-08-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |