| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_85b959d2100bb308fcf773d125a37ab8
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a0113b37caab3e120aace5a21cd971a9
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_40b922ff081632b6c633ff8dc46fb7c5
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_89a8aa9db8074e7174d76f88e9106f25
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_6436bcba24723aaacc2c0c1aa46dfef1 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y304-24027 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H21-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K17-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-54
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-96 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-96 |
| filingDate |
2012-06-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fa0389ab98c35572dc2d8b9f68afd4cf
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f99a1f952f6246f9621826a0fa0da41e
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_58ba98f23c4e752ec90584e7c9dae026
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0c30062d1bf2a4a202c97f67cabd356d |
| publicationDate |
2012-09-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-2012244598-A1 |
| titleOfInvention |
Stabilization of Thermolysin in Aqueous Solution |
| abstract |
The present invention deals with the proteolytic enzyme thermolysin which tends to be unstable in aqueous solution. The invention provides methods and compositions to enhance the stability of dissolved thermolysin in aqueous solution. Thermolysin, crude thermolysin or a lyophilisate containing thermolysin and one or more salts, is contacted with an aqueous buffer with a low salt concentration and a first solution is formed. Subsequently, a further salt in solid form is added and dissociated, thereby forming a second solution comprising thermolysin in a stabilized form. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11359190-B2 |
| priorityDate |
2008-08-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |