| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_806fe13dd4f23bbbbebfb649c6c85d03
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ddbdb9fc5f2c82de19c56789faa5bbaa
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_b20e52f815f0f7dda57e5dfcbf25eecf
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2e3830f35387a1c32061dea3ee310851 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2710-10032
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2750-14143 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P13-12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N7-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-86
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K48-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K48-0075 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K35-76
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-864
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P13-12 |
| filingDate |
2010-09-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a19907a002efa359ae7e62d548921027
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2bf34e2cf48da718c5936acf6b2dbde5
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_038e4110a040f0ad0157460d96cb9113 |
| publicationDate |
2012-09-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-2012244127-A1 |
| titleOfInvention |
AAV Vectors Expressing SEC10 for Treating Kidney Damage |
| abstract |
A method for enhancing repair of damaged mammalian tubular epithelial cells involves delivering to the tubular epithelial cells of a subject in need thereof a composition comprising an adeno-associated virus (AAV) comprising an AAV capsid having an amino acid sequence of a selected AAV serotype, and a minigene having AAV inverted terminal repeats and a Sec10 gene operatively linked to regulatory sequences that direct expression of Sec10 in the epithelial cells. In one embodiment, delivery is accomplished by retrograde intrauretal injection. In an embodiment the AAV vector includes a capsid of AAV serotype 2/8. Therapeutic compositions containing such AAV are provided. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2022251060-A3
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9249425-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10610606-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9896665-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11306329-B2 |
| priorityDate |
2009-10-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |