| abstract |
The present disclosure relates to a series of substituted N-phenyl-bipyrrolidine carboxamides of formula (I): n n n n n n n n n n wherein R 1 , R 2 , m, n and p are as described herein. More specifically, the compounds of this invention are modulators of H3 receptors and are, therefore, useful as pharmaceutical agents, especially in the treatment and/or prevention of a variety of diseases modulated by H3 receptors including diseases associated with the central nervous system. Additionally, methods of preparation of substituted N-phenyl-bipyrrolidine carboxamides and intermediates therefore are disclosed. |