Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_eead910f15d5f1f1dc8b54ea55084da3 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a6002fbe630644625bdb02314726ae64 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_7ccb011ca7093c4cd0d3a3c38852a656 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2c7d26faa7022f3bdd6eed6bd55fcd6a http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a7c05b480c830c0e092b58164c259df4 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-622 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P21-005 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-163 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-16 |
filingDate |
2011-10-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6ba07d11591d51135c6ee7551bf38a21 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f2f03e94f7139ecf42283a1da53757aa http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3a52906d1fb24d145300a3bf742f6768 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_00962f3cd3bd1f0cdaebe1daba7ac633 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_833bac07e5875eb1ff31068a05705930 |
publicationDate |
2012-09-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-2012238013-A1 |
titleOfInvention |
Fusion partner for production of monoclonal rabbit antibodies |
abstract |
The invention provides a rabbit-derived immortal B-lymphocyte capable of fusion with a rabbit splenocyte to produce a hybrid cell that produces an antibody. The immortal B-lymphocyte does not detectably express endogenous immunoglobulin heavy chain and may contain, in certain embodiments, an altered immunoglobulin heavy chain-encoding gene. A hybridoma resulting from fusion between the subject immortal B-lymphocyte and a rabbit antibody-producing cell is provided, as is a method of using that hybridoma to produce an antibody. The subject invention finds use in a variety of different diagnostic, therapeutic and research applications. |
priorityDate |
2005-07-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |