Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_aa03b54c1e2494223917c9bd9e5edde8 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_584666f2b0a05e89725ca5794c85e904 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_405ec8b95ea2f1d380fcc9c183a106a7 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_6c92d4a62df5f94768694363768d0a0a http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_638336aa54551464013be94ef40d5fb0 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2710-16222 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-005 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N7-00 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P21-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-10 |
filingDate |
2010-09-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2b8019eb014c16e95637e07ef64a43c3 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2640c760004d5eb1f9d3f71f6407f63b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_21ec70cf1dadaba6650e7b6c94e95ff5 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_660ae99f02f15fe7c7273ace482795f7 |
publicationDate |
2012-09-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-2012231500-A1 |
titleOfInvention |
Cells For Transient Expression And Uses Thereof |
abstract |
This invention relates to the transient expression of heterologous polypeptides in mammalian cell lines. Specifically it relates to an expression-enhanced cell line derived from a parent cell line, the expression-enhanced cell line comprising nucleic acid encoding Epstein-Barr Virus Nuclear Antigen 1 or a functional derivative, analogue, or variant thereof; and further comprising:n (a) a nucleic acid encoding an exogenous glutamine synthetase; (b) a nucleic acid encoding an endogenous glutamine synthetase, wherein the endogenous glutamine is arranged to have enhanced enzymatic activity and/or enhanced expression relative to the parent cell line under comparable conditions; or (c) both (a) and (b). |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2018518985-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9550972-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10774353-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-113981027-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10494421-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-108138214-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10131868-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2016176275-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2021137015-A |
priorityDate |
2009-09-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |