abstract |
A detection device and method for detecting one or more analytes of interest in a test sample are provided. Some embodiments use analyte-specific binding partners that are conjugated to quantum dots (Qdots) for use in detecting the presence and/or quantity of the analytes of interest in a test sample. FRET based methods may to used enhance the quantum dot (Qdot) signal through complexing of the quantum dots with lanthanide chelates, such as terbium. Some embodiments of the invention provide a novel disposable testing device that contains, all in one, the components necessary for carrying out the novel assay detection system of the invention. The disposable testing device may be used at home, for example, to detect and quantitate, at ultrasensitive levels, multiple analytes in a biological sample with no requirement for professional assistance. |