| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_1885aef56728928741ae76d9f7e30d37
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d1efc6cbf4bed172beb741676e4dd4db |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K51-08
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K1-13
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D327-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K51-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K51-082 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C309-24
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D411-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C303-02 |
| filingDate |
2010-08-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1b3c540afac496752c8a38af7750733b |
| publicationDate |
2012-08-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-2012220785-A1 |
| titleOfInvention |
Sultone compound derivatives substituted by nucleophiles, in particular radionuclides, and use thereof for marking macromolecules |
| abstract |
The invention relates to polysultone derivatives used as precursors to radiolabelled macromolecules usable for medicine and in nuclear imaging. The aim of the invention is to provide novel prosthetic compounds or groupings, the synthesis of which is straightforward, easy and automatable, enabling access to economical and effective radiolabelled macromolecules. The aim is achieved by the invention, which involves compounds of formula 10 or 11. Said double-sultone derivatives are produced by opening the sultone rings using a nucleophile radical R i which may be a radionucleide R* for one of the sultone rings and an active radical peptide R a for the other sultone ring. The invention also relates to the method for producing the abovementioned compounds, as well as to the drugs or diagnosis products that the latter are capable of forming. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9263766-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9748607-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10199686-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9912010-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2015086861-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9847554-B2 |
| priorityDate |
2009-08-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |