Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_f16b689234fc9c77a964731c8861871b http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_671e98af894d0589b7f4585147c37f4f http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_1225b79f5122e7db181c4fa25f3cf9be http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_fbbac5978c7c88442fdb6062e1a5a834 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-1272 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-1271 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K33-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-127 |
filingDate |
2010-10-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c069a4d1f6a46684a3b29d0512408603 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_99c8d907ec761b937a1638fffb3b02de http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f40de914c74b20fae17d3af568304d79 |
publicationDate |
2012-08-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-2012219618-A1 |
titleOfInvention |
Spla2 hydrolysable liposomes with improved storage stability |
abstract |
The present invention provides a composition comprising a sPLA2 hydrolysable liposome, an exterior solution, and an interior solution within the liposome, -wherein the concentration of osmolytes is higher in the interior solution than in the exterior solution. The composition improves storage stability of sPLA2 hydrolysable liposomes, in particular at when stored at 2-8 degrees Celsius. The liposome preferably encapsulates cisplatin. The invention also provides methods of preparing the composition of the invention. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2021212947-A1 |
priorityDate |
2009-10-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |