Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_7cc95199cc0beea5482a80ad106fe7d5 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_9adab9f0493ca34f215d5075695fc7ad http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_3a45706f5f8d6bf8849619948eb3255b http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_8207c6838679f66396d6c497afc76426 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d8e175da12afeeae2b1a870a8eaab577 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2021-6432 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2021-6439 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-533 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-582 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N21-6428 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D487-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D498-22 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N21-76 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D471-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D401-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F5-00 |
filingDate |
2010-08-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5a43f441dadb92d849cdce2822440997 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0d08315b8d12d4fe38860104abaf056e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_15e368e6e0640dff3a28a1d7473afc33 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7fb12950c19ff90a43fe281fb2123333 |
publicationDate |
2012-08-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-2012214253-A1 |
titleOfInvention |
Macrocyclic hopo chelators |
abstract |
The present invention provides a novel class of macrocyclic compounds as well as complexes formed between a metal (e.g., lanthanide) ion and the compounds of the invention. Preferred complexes exhibit high stability as well as high quantum yields of lanthanide ion luminescence in aqueous media without the need for secondary activating agents. Preferred compounds comprise hydroxypyridinonyl moieties within their macrocyclic structure and are characterized by surprisingly low, non-specific binding to a variety of polypeptides such as antibodies and proteins as well as high kinetic stability. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10082387-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11453652-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10352938-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11603371-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2017261313-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10239878-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2018045385-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2011189088-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9556122-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9273059-B2 |
priorityDate |
2009-08-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |