Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_6747b2d25117dab20d36ee3569d0a32f http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_716e9a2606ffd4ba1a2a3917e4a402fd http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_b30a9f53e7b924f79c11a9877439609e |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2510-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2501-608 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2501-603 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2501-604 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2501-602 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-0696 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-90 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-071 |
filingDate |
2010-09-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_527afb06ab729be52b011f31f1bfbc43 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f7da87646d2635a846fcfb66837b431c |
publicationDate |
2012-08-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-2012214243-A1 |
titleOfInvention |
Method of efficiently establishing induced pluripotent stem cells |
abstract |
Provided are a method of improving iPS cell establishment efficiency, comprising the step of transferring Lin28B or a nucleic acid that encodes Lin28B to a somatic cell, particularly to a somatic cell on which Lin28 is ineffective or less effective than Lin28B in improving iPS cell establishment efficiency, and a method of producing an iPS cell, comprising the step of transferring Lin28B or a nucleic acid that encodes Lin28B and a nuclear reprogramming substance to a somatic cell. Also provided are an iPS cell comprising a nucleic acid that encodes Lin28B, that can be obtained by the method of producing an iPS cell, and a method of somatic cell production by forcing the iPS cell to differentiate into a somatic cell. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11525119-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2018156903-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2021150919-A1 |
priorityDate |
2009-09-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |