| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_9d861fb19e84f2271f9655c1ff74dc9d
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_0736f2ef291cec7526de02eaf5d9e5e1
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_0e82840882ffb5112f80567bf328c399
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_6416e2d0768b299c3109fb0325b1a538
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_12a9e9ce63eb0bbf3658453fb50a6d9b
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_41e556a1ac74900bce31d1449bc197d0 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-14
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-141 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-63
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-67
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-113
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P21-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P21-00 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P21-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-85 |
| filingDate |
2010-05-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f6c7e18d751e147098c801ee089a5b92
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_26d5d6efc6d83f69884932494cbac2ef
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_695e5494cc8ac14b319b8b447a1b7b66
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8613a9029729e72b4332a7548510921d
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ff6340ae94df8d85fe3ff555cc5dec26 |
| publicationDate |
2012-07-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-2012190065-A1 |
| titleOfInvention |
Combinatorial engineering |
| abstract |
The invention concerns the field of cell culture technology. It concerns production host cell lines with increased expression of ribosomal RNA (rRNA) achieved through introduction of nucleic acids encoding UBF or reducing expression of NoRC proteins, especially of TIP-5. Those cell lines have improved secretion and growth characteristics in comparison to control cell lines. The invention further concerns a method of producing proteins using the cells generated by the described method. |
| priorityDate |
2009-05-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |