| abstract |
This invention provides the compound having the structure n n n n n n n n n n n n wherein n n is 1-10; n X is C—R 11 or N; wherein R 11 is H, OH, SH, F, Cl, SO 2 R 7 , NO 2 , trifluoromethyl, methoxy, or CO—R 7 , wherein R 7 is alkyl, alkenyl, alkynyl, C 3 -C 8 cycloalkyl, or aryl; n Z is n n n n n n n n n n n n n n n n R 2 is H or NR 3 R 4 , wherein R 3 and R 4 are each independently H, C 1 -C 6 alkyl, or C 3 -C 8 cycloalkyl; n R 5 is OH or SH; and n R 6 , R 12 , R 13 , and R 14 are each independently H, OH, SH, F, Cl, SO 2 R 15 , NO 2 , trifluoromethyl, methoxy, or CO—R 15 , n wherein R 15 is alkyl, alkenyl, alkynyl, C 3 -C 8 cycloalkyl, or aryl, or n a salt of the compound,n nwhich is useful in the treatment of tumors. |