| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_bd44bf58917f2d0759fa55f2b6c327e5
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_81013e05048c1896a39568dcf0e89daf
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_71b944100daf03103e6704d7474fd127
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_57339361bde86b327144e94027a13306
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_fd45b221a2b473399c5c3b5d5f571dd0 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2800-323
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-55
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2800-324
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-21
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-33 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-6854
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-6893
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-18
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-1203 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C40B30-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-53
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-554 |
| filingDate |
2012-01-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2dffb6411c7a98a0aed6a01666478202
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3d207bc9bd4c92974f8630305e425a12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_60febb2dc1978161c992ec691bef6ed9
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b820e1abcca8eb61aeb658abed8ca0a7 |
| publicationDate |
2012-06-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-2012165211-A1 |
| titleOfInvention |
Human Antibodies Cross-Reacting With A Bacterial And A Self Antigen From Atherosclerotic Plaques |
| abstract |
The present invention refers to human antibodies derived from human antibody libraries prepared from atherosclerotic plaques. It further refers to human antibodies able to immunologically recognize both human transgelin or fragments thereof and a protein with at least 50% similarity to OmpK36 (Outer membrane protein, Klebsiella, K36; GI: 295881594) or fragments thereof. Human transgelin is preferably transgelin 1 (Accession N° Q01995, GI:48255907). The antibodies further recognize an antigen in the atherosclerotic plaque and are useful for the preparation of immunodiagnostic reagents or assays to detect atherogenic diseases. The invention also relates to the use of anti-TAGLN monoclonal antibodies, showing cross-reactivity with a bacterial antigen having at least 50% similarity with OmpK36, for detecting antigens in the atherosclerotic plaque or as atherosclerotic related reagents in an immuno-competition assay. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-102371151-B1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-20210115435-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2021182929-A1 |
| priorityDate |
2007-09-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |