http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2012157708-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_f9a0a4a9748f1b5f0df8d23aeb1e2491 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_0d44cd5ef81505620099ae7acf1dc404 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C41-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C51-15 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C59-315 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C67-31 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C59-305 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C51-367 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C67-31 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C231-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C41-22 |
| filingDate | 2010-08-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_02a6b0a4dd21c46a7a04a7e8602a0be6 |
| publicationDate | 2012-06-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | US-2012157708-A1 |
| titleOfInvention | Process for the manufacture of sevoflurane |
| abstract | A process for the manufacture of Sevoflurane CF 3 —CH(OCH 2 F)—CF 3 which comprises (a) manufacturing a substituted malonic acid derivative of formula (I): R 1 OOC—CH(OCH 2 X)—COOR 2 or of formula (II): R 3 HNOC—CH(OCH 2 X)—CONHR 4 , wherein X is OH or a leaving group which can be substituted by nucleophilic substitution and wherein R 1 , R 2 R 3 , R 4 , equal to or different from each other, are independently selected from the group consisting of H, an alkyl group having from 1 to 10 carbon atoms which is optionally substituted by at least one halogen atom, an aralkyl group, and an aryl group; and (b) further reacting said malonic acid derivative as intermediate for the manufacture of Sevoflurane CF 3 —CH(OCH 2 F)—CF 3 . |
| priorityDate | 2009-08-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 124.