| abstract |
The present invention relates to a compound of formula (I) or a pharmaceutically acceptable salt thereof, wherein R 1A , R 1B , R 1C , R 2 , R 3 , R 4 , R 5 , R A , R B , R C and X are as defined herein. These novel benzimidazole derivatives are useful in therapy, in particular for treating diseases or conditions mediated by SMO, including the treatment of abnormal cell growth, such as cancer, in mammals. This invention also relates to a method of using such compounds in the treatment of abnormal cell growth in mammals, especially humans, and to pharmaceutical compositions containing such compounds. |