| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_6782244879e81710bdd3b7dd774012ed
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_f1ae3fa35e66a7c881c8dcb479e1d114
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_3987e1fded18a96166ed3aaddaa2abe2
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ad46d1814cdda406228b2ce12b8d0f2f
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_e2e10790bf9803ec5945181d01f19c71 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2800-52
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y10T436-25625
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y10T436-25
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y10T436-24 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-6848
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-6803
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-57426
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-6851 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-68
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-574
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/H01J49-26 |
| filingDate |
2011-12-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4ec54c844b7bf7abdc45ebd94bc7db54
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cc4da3b51910fb5a35b3fff4cdf23812
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_78ecf42c46fcf78b0e1d7bc12c993233
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_77056942552ddd39c622cbf817efc0f8
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0871d8b7028d490364d752e777649745 |
| publicationDate |
2012-06-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-2012145891-A1 |
| titleOfInvention |
Using Plasma Proteomic Pattern For Diagnosis, Classification, Prediction Of Response To Therapy And Clinical Behavior, Stratification Of Therapy, And Monitoring Disease In Hematologic Malignancies |
| abstract |
The present invention demonstrates that the diagnosis and prediction of clinical behavior in patients with hematologic malignancies, such as leukemia, can be accomplished by analysis of proteins present in a plasma sample. Thus, in particular embodiments the present invention uses plasma to create a diagnostic or prognostic protein profile of a hematologic malignancy comprising collecting plasma samples from a population of patients with hematologic malignancies; generating protein spectra from the plasma samples with or without fractionation; comparing the protein spectra with clinical data; and identifying protein markers in the plasma samples that correlate with the clinical data. Protein markers identified by this approach can then be used to create a protein profile that can be used to diagnose the hematologic malignancy or determine the prognosis of the hematologic malignancy. Potentially these specific proteins can be identified and targeted in the therapy of these malignancies. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-109507347-A |
| priorityDate |
2004-04-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |