Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_bed67829573eda8797645cf289de60b7 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_4283870231c7561bf863a2172d86c57b http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_52a9e5415cef3798012dc0a319deeb1c http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_0938e84d8ac1ea5eb8623c57288253a4 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_b2819bf1753f62cace0cbc38326446d5 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08L89-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P19-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P19-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-3604 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-3687 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08H1-00 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K1-02 |
filingDate |
2012-02-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cfb80ca1e9ea971e8171c8878c26735b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4b9e609cda4b1aa7d6888b0047c9ee4d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7b3841453773f25fa5d9b2f789e66685 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bbd6a0849643716190ca03b23e2ac9f2 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6cac6ac6b8ab4a323cdc9b6b6ed35792 |
publicationDate |
2012-06-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-2012142898-A1 |
titleOfInvention |
Implantable material and a method for the preparation thereof |
abstract |
A method for the preparation of a regenerated silk fibroin solution comprises the steps of: treating silk or silk cocoons with an ionic reagent comprising an aqueous solution of monovalent cations and monovalent anions, the cations and anions having ionic radii of at least 1.05 Angstroms and a Jones-Dole B coefficient of between −0.001 and −0.05 at 25° C.; and subsequently degumming the treated silk or silk cocoons; or alternatively, degumming silk or silk cocoons; and subsequently treating the degummed silk or silk cocoons with an ionic reagent comprising an aqueous solution of monovalent cations and monovalent anions, the cations and anions having ionic radii of at least 1.05 Angstroms and a Jones-Dole B coefficient of between −0.001 and −0.05 at 25° C. The invention also extends to fibroin solution, a fibroin material and an implant useful for cartilage repair. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-110944682-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-3641840-A4 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2483756-C1 |
priorityDate |
2008-04-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |