| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d21cbff64022f95c237c0bd3ec8656ca
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_c05d02203d6b3234ce6f257dfc3edb8f
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d5cba611a35853dffda3861a173a1e53 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2533-90 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-0665
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-0662
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-24
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N1-38 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-0775 |
| filingDate |
2009-06-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_866ceb2f1b74ae21271f27cd33f51405
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e2059c195dee5bc6eb10c8cf9144ac28 |
| publicationDate |
2012-06-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-2012142102-A1 |
| titleOfInvention |
Isolation of human umbilical cord blood-derived mesenchymal stem cells |
| abstract |
Human umbilical cord blood (UCB) contains mesenchymal stem cells (MSCs) that have higher multipotentiality than adult marrow-derived MSCs. However, it has been difficult to obtain these cells because the frequency of MSCs in UCB is extremely rare (0.4-30 out of 1×10 8 mononuclear cells). To date, the isolation of MSCs has depended upon their plastic-adhesion capacity. Some “true” MSCs could be missed because their ability to adhere to plastic may be poor. Previous studies demonstrated extracellular matrix (ECM) made by bone marrow cells enhanced MSC attachment and proliferation, and retained their stem cell properties. The present invention provides methods for isolating MSCs from umbilical cord blood by adherence to an ECM and uses for the isolated stem cells. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9795707-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9744266-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9801975-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9801976-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2017123312-A2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10772986-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2021076043-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11180732-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9358320-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8940294-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2017168343-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11446334-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11220671-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9616152-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11229725-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11542473-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2016070057-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2018008531-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10842910-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9480549-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10568990-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9446077-B2 |
| priorityDate |
2009-03-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |