http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2012142075-A1
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_f89d315e735f86d49baddc1c48010de4 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_13b9a401a417324112da1d7b7ff76e24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ad77a3e0637555c10dc9bfa902862e2c http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_6b06f4620c421c324204eac76e02cc8b |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-58 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-58 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-76 |
filingDate | 2012-02-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e28ed38c0b28c21b8b777209c0e03b78 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c1da6e08d842258c51dfcb41230ec307 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_33ed53ae3d4b55dc3fb1db7f3ee156de |
publicationDate | 2012-06-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | US-2012142075-A1 |
titleOfInvention | Microbial Trypsin Mutants having Chymotrypsin Activity And Nucleic Acids Encoding Same |
abstract | The present invention relates to microbial trypsin variants having chymotrypsin-like activity, comprising: (a) a one or more substitutions corresponding to positions 144, S193, 198, 201, 218, 223, 227, 228, 229, 230, and 231 of amino acids 25 to 248 of SEQ ID NO: 2, (b) one or more deletions corresponding to positions 192, 197, and 226 of amino acids 25 to 248 of SEQ ID NO: 2; and (c) an insertion between positions corresponding to positions 224 and 225 of amino acids 25 to 248 of SEQ ID NO: 2. The present invention further relates to nucleotide sequences encoding microbial trypsin variants having chymotrypsin-like activity; nucleic acid constructs, expression vectors, and recombinant host cells comprising such nucleotide sequences; and methods of producing microbial trypsin variants having chymotrypsin-like activity or a precursor thereof. |
priorityDate | 2002-09-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 436.