| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_705cc3aafb38bd03db7a7c4366118de8
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_adf225ca4a6bf6190b6a2763410d1ebf
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d13f5c7c44a0b147c2abd01d243e0b64 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08J2467-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08J2300-16
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08J2367-04 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-192
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01J13-125
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-5089
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08J3-126
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08J3-16
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08J3-14
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-5026
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-5031
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-5073
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C09B67-0097 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-14
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-34
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-32
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-395
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C05F11-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-43
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-7088
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C09B67-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-18
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A01N25-26 |
| filingDate |
2010-06-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9c706b7fb5640b7cd3a99a2f5566425f
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e324d23691bba095354a5377439d54d6 |
| publicationDate |
2012-05-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-2012128752-A1 |
| titleOfInvention |
Multi-phase microparticles and method of manufacturing multi-phase microparticles |
| abstract |
The invention relates to a method of manufacturing multi-phase microparticles. The method comprises dissolving at least three different polymers in a volatile organic solvent to obtain a first solution. The first solution comprises at least two cloud points, wherein the second cloud point is higher than the first cloud point. Viscosity of the first solution and the first and second cloud point are selected such that the at least three different polymers are immiscible with each other in the first solution. The first solution is dispersed into an aqueous continuous phase which comprises a surfactant to obtain an emulsion. The volatile organic solvent is evaporated from the emulsion. The total concentration of the at least three different polymers together in the emulsion before evaporation is below the first cloud point, or is above the first cloud point and below the second cloud point or is above the second cloud point. The invention relates also to a multi-phase microparticle made by the method and a pharmaceutical composition comprising the multi-phase microparticle. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2019173062-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11344502-B1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11571674-B1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11542392-B1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11547978-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2020086940-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11484857-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2015051179-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11007501-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11465117-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9862807-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10285940-B2 |
| priorityDate |
2009-06-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |