| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_c26deadac2a7ce4c4a51f88b4184b07a
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_74187bd24d0e86b8762f09842b22cc64
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_c6f8330952c06384eda146aca46ec1b7 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-47
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P7-06 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A01K67-027
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-63
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-16
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H21-04 |
| filingDate |
2009-12-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_34b2053fa11c58ddfa05c7038ed272a3
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3444486a2f4d3b68cc7c897ab61a6c6e |
| publicationDate |
2012-05-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-2012124684-A1 |
| titleOfInvention |
Compositions and methods using alpha beta-crystallin in protecting the myocardium from ischemia/reperfusion injury |
| abstract |
The invention provides a modified version of alpha B-Crystallin (αBC), and methods for delivering this modified version of alpha B-Crystallin (αBC) to tissues and cells; the invention provides a modified version of αBC in which the serine at position 59 has been changed to glutamate to mimic phosphorylation and the serine at positions 19 and 45 have been changed to alanine to prevent phosphorylation of those residues. The invention also provides compositions and methods for ameliorating a cell from ischemia/reperfusion injury or protecting a cell from ischemia/reperfusion injury. |
| priorityDate |
2008-12-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |