| abstract |
The present invention relates to the use of a compound of the following formula (I) for detecting a peptidase activity and/or a variation in pH: n n n n n n n n n n according to which:n Y 1 is a peptide, H or an alkyl; W 1 , W 2 , W 3 and W 4 are independently H, Br, Cl, F, I, alkyl, alkoxy, thiomethyl, perfluoroalkyl, nitro, cyano, carboxyl (including the esters or amides thereof) or any combination thereof; n=0, 1 or 2; U and V are N, N + R or CZ 4 , R being H, alkyl, aralkyl, aryl, alkanoyl or alkylsulfonyl; Z 1 , Z 2 , Z 3 and Z 4 being independently H, Br, Cl, F, I, alkyl, aryl, alkoxy, perfluoroalkyl, nitro, cyano, carboxyl, sulfonyl, including the carboxyl or sulfonyl esters or amides,n nand salts thereof. |