| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_c2f83b007ff3c1dde2c1dd1eb6a477a3
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2ac3830c836a5f125f4b91495c33509c
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_20dd1c1dde2e19fd696135beee47b398
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_717c792fca7cc9c290c9db33e8fe078b
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_e51269baecd1cee60fe19e0a802e1663 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y10T428-2982
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B82Y5-00 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K49-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K49-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K49-08
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K49-126
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K49-1854
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B82Y5-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K49-1857
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K49-1863
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K49-186 |
| classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B82Y40-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B82Y5-00 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C01G45-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K49-12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K49-14
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K49-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K49-16 |
| filingDate |
2008-01-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_938ca2b03ed4c2469542ff8399d91a65
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_34fab9bb2ad1a85532fc265074b751ab
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d44e1b3e1bc9dee82eefeeb212059d58
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_017894949e0fab1faa14ac3a3bcc9f65 |
| publicationDate |
2012-05-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-2012114564-A1 |
| titleOfInvention |
Mri t1 contrasting agent comprising manganese oxide nanoparticle |
| abstract |
The present invention relates to the use of and method for using MnO nanoparticles as MRI T1 contrasting agents which reduces T1 of tissue. More specifically, the present invention is directed to MRI T1 contrasting agent comprising MnO nanoparticle coated with a biocompatible material bound to a biologically active material such as a targeting agent, for example tumor marker etc., and methods for diagnosis and treatment of tumor etc. using said MRI T1 contrasting agent, thereby obtaining more detailed images than the conventional MRI T1-weighted images. The MRI T1 contrasting agent of the present invention allows a high resolution anatomic imaging by emphasizing T1 contrast images between tissues based on the difference of accumulation of the contrasting agent in tissues. Also, the MRI T1 contrasting agent of the present invention enables to visualize cellular distribution due to its high intracellular uptake. The MRI T1 contrasting agent of the present invention can be used for target-specific diagnosis and treatment of various diseases such as tumor etc. when targeting agents binding to disease-specific biomarkers are conjugated to the surface of nanoparticles. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2016089455-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-115072785-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-3037107-A4
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9765187-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9801958-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-3037107-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2014163221-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11497809-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-115137823-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2015149188-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-106596617-A |
| priorityDate |
2007-01-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |