| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_01396215308486fb20e9dd2f95037972
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2c3c5dd1d8582b366503230ab4d8a29d
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_e5c9de6bba5aeb0f576490bd5add7dde |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6841 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6837
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6827
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B82Y15-00 |
| classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B82Y15-00 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-543
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-553
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C40B30-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C40B50-14
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C40B60-12 |
| filingDate |
2010-10-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_20ff65e5bf3a289d7afe8f5cdc5b4a23
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_404f6f70e27b3d7c58a39f11dd66e3c4 |
| publicationDate |
2012-05-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-2012108451-A1 |
| titleOfInvention |
Methods and apparatus for nanoparticle-assisted nucleic acid hybridization and microarray analysis |
| abstract |
The invention provides nucleic acid hybridization methods for detecting target nucleic acid sequences wherein complexes comprising nanoparticles non-covalently associated with single-stranded tartlet nucleic acid molecules are incubated with immobilized probe nucleic acid molecules. Because the nanoparticles function as competitors in the hybridization reaction between the target nucleic acid molecules and the probe nucleic acid molecules. The methods provide a high degree of discrimination between a perfectly matched target sequence and a sequence having at least a single-base-pair mismatch, even when the hybridization reaction is performed at room temperature. The invention also provides microarray methods and apparatus which incorporate the nanoparticle-assisted hybridization methods. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-112795628-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10465236-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10239122-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-104372089-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-112522406-A |
| priorityDate |
2010-10-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |