Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_63365fd9181678ddf2f800d003c56b0d http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_1ba6c2fc3f40eccda7665fbb5a961f41 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_e6063c8ea66ba6e01d8f71f73c4fed3c http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_c00414b14c3bb8a548a9e44d459dc905 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2800-50 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2770-36143 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2820-60 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-5258 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2800-40 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P37-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-86 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-85 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K48-0041 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-005 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P37-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P19-34 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H21-02 |
filingDate |
2009-11-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8df8f04a2dee7e6e0bcd6ae1a8693d11 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b3c4868d83942e7badffac44d46c23fc http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7b2c9b202aa4f62839d90e3b6f31e9e8 |
publicationDate |
2012-04-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-2012100179-A1 |
titleOfInvention |
Use of micrornas to control virus helper nucleic acids |
abstract |
Provided herein are helper nucleic acids comprising at least one microRNA target sequence of an endogenous, cellular microRNA and a nucleic acid encoding a viral protein, wherein the microRNA target sequence is located in the untranslated or translated region of the nucleic acid encoding the viral protein. Also provided are vector systems, compositions and cells comprising the provided helper nucleic acids and a vector or replicon. Methods of making virus-like replicon particles and populations of virus-like replicon particles (VRP) are also provided. |
priorityDate |
2008-12-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |