http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2012095230-A1
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_59a4bca1c50802c99896fdfc3329b352 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_51d6f4d54509dfde6a832d7ad2baf3aa |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D239-42 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C253-20 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C253-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D239-42 |
filingDate | 2010-04-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ed82e78a9b992ae0b65988cbd9c455c6 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a6c3e07d2f7c86c59221302bd4da80dd |
publicationDate | 2012-04-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | US-2012095230-A1 |
titleOfInvention | Process for the preparation of pyrimidine derivatives |
abstract | A process for the preparation of 5-substituted 4-amino-2-methylpyrimidines of the formula (I) wherein R is CONH 2 or CN, and of acid addition salts thereof, characterized in that a compound of formula H 2 N CH═C(R) CN (II) is reacted with acetimidic acid methyl ester or an acid addition salt thereof and that, if desired, a compound of formula (I) is transferred into an acid addition salt, and the transformation of a compound of formula (II) wherein R is CONH 2 into a compound of formula (II) wherein R is CN by treatment with POCI 3 . |
priorityDate | 2009-04-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 80.