Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_315f9ce39ec903ef501f145287089892 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_f8fa486c00ac33582c41e9dd2fe443e7 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_c73af51e2d45af026d431c53f0eaf42a http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_06b9da69626ed1dd1f9c8b1b7447e433 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_9327cf5b1c428774e224958a5c590129 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y10S977-918 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y10S977-788 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y10S436-807 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y10S435-81 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y10S977-773 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y10S977-70 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-54388 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-558 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K1-107 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-558 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-53 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-70 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-46 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-577 |
filingDate |
2011-06-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_89f609c45698c90626881446c489cee4 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9d241984442bf45b0275336348449f05 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8d4ba5cacdaee717e2ed7778dd5b8d9c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_dd384305b1547a2be2bc9dd70ed8e99d |
publicationDate |
2012-04-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-2012094272-A1 |
titleOfInvention |
Signal enhancement system with multiple labeled-moieties |
abstract |
Dipstick tests for detecting analyte are described. In a preferred embodiment, a multiple biotinylated antibody capable of binding analyte is bound to an anti-biotin antibody labelled with colloidal gold and wicked up the dipstick with test solution thought to contain analyte. Complex formed between analyte, biotinylated anti-analyte antibody, and colloidal gold labelled anti-biotin antibody is captured at a capture zone of the dipstick. Presence of colloidal gold label at the capture zone indicates the presence of analyte in the test solution. The sensitivity of analyte detection using such methods is an order of magnitude higher than for comparable methods in which biotinylated anti-analyte antibody bound to analyte is wicked up the dipstick in a first step, and a colloidal gold labelled anti-biotin antibody is wicked up the dipstick in a separate step. Kits for performing the tests of the invention are also described. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-108872611-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2020128908-A3 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2011076697-A1 |
priorityDate |
2000-11-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |