abstract |
The invention relates to compounds having the formula: n n n n n n n n n n wherein: Ar, r, R 3 , Z, X, and R 5-7 are as defined in the specification, or a pharmaceutically acceptable salt thereof. These compounds have AT 1 receptor antagonist activity and neprilysin inhibition activity. The invention also relates to pharmaceutical compositions comprising such compounds; methods of using such compounds; and process and intermediates for preparing such compounds. |