| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ea3fa97ed2bcf7f6b9f5ea5a3d32cb13
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_f8ac5e6870b9bf3a71cb5ee74c668422
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_f8467e2b91e5f2f759334e924646c129
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_06a0a8b3fcf088e123eea72337fc1cdc
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_28529ffcd1c811c3560bb695c4af5209
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_79b466af77c82db892f58044a6a10765
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_eee90c60f16a941b5235a89e19129849 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08G69-48
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K1-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07F15-025
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07F15-045
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07F15-065 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K2-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-34
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08B37-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B29C67-24
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08G69-48
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F15-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08J3-205
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F15-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H21-00 |
| filingDate |
2011-03-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6c8aa956efb87bba575c56831136345a
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d4f9cf55b4efe46caaa0efbf0bc220ec
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c7c11e202a29e7d98fd81df379fe120a
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_43690c917547c3dba2ffbb001c27a329
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7807587410d341f28a9b07153b8f1645
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cdfbb01142686ffd09dab9179e218a00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_78b9e62ca6de33a8a70b5e7a20a3323b |
| publicationDate |
2012-04-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-2012088848-A1 |
| titleOfInvention |
Methods and compositions for controlled polypeptide synthesis |
| abstract |
Methods and compositions for the generation of polypeptides having varied material properties are disclosed herein. Methods include means for initiating the polymerization of aminoacid-N-carboxyanhydride (NCA) monomer by combining the monomer with an amido-containing metallacycle, for making self assembling amphiphilic block copolypeptides and related protocols for adding oligo(ethyleneglycol) functionalized aminoacid-N-carboxyanhydrides (NCAs) to polyaminoacid chains. Additional methods include means of adding an end group to the carboxy terminus of a polyaminoacid chain by reacting an alloc-protected amino acid amide with a transition metal-donor ligand complex to forming an amido-amidate metallacycle for use in further polymerization reactions. Novel compositions for use in peptide synthesis and design including five and six membered amido-containing metallacycles and block copolypeptides are also disclosed. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-108368260-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8278111-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8252595-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-114585664-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9187735-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-3392291-A4
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8975082-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11174288-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9096652-B2 |
| priorityDate |
1998-03-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |