http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2012077704-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_045afb78270bfd7fee6080a3ab34c8b9 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_5fc41babbd645579754015dbd021a609 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-5041 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-5014 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C40B30-04 |
| filingDate | 2010-06-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ec75cdcaaa7b6c95d17058452993859a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_33fe4dbe0a64fee11a194092752d5536 |
| publicationDate | 2012-03-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | US-2012077704-A1 |
| titleOfInvention | Method for screening compounds for the treatment or prevention of colon cancer |
| abstract | The invention is in the field of molecular medicine, more in particular in the field of identifying new compounds for the treatment or prevention of colorectal cancer. The invention provides a method for the screening and/or identification of compounds that are capable of preventing or ameliorating the adverse effects of reactive oxygen species on eukaryotic cells. More in particular, the invention provides a method for the identification of an active therapeutic compound for preventing or ameliorating the adverse effects of reactive oxygen species on eukaryotic cells comprising the steps of: providing an assay wherein the expression of the WNT pathway in Caco cells can be determined under the influence of a reactive oxygen species, providing a candidate therapeutic compound, determining the ability of said therapeutic compound to normalize the expression of said WNT pathway in the presence or absence of said oxidant. |
| priorityDate | 2009-06-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 1074.