| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ea94d18f2d42840316f0f1e9a207d24b
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_62b7087ea1b241dbbabeca799d1253ce
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_76e6dcda2d334508ba91bffed8766130
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2a819eda0adf22936a52362eeebb9fb4 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-14
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-141
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2740-16011
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-531
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2320-32
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2320-31
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2740-16043
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2740-16051 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-18
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N7-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-1138
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K48-0066
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-86
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-7105
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-53
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-7158
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y603-02 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N7-01
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-18
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-63
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-70
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-071
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K48-00 |
| filingDate |
2010-04-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d3446fd1aba0bb48fb1bd640e73f496a
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b060156f23784c87968c07f5536c9ed5
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_803ddaad58e17b14ef2ce7e8f83f92e2 |
| publicationDate |
2012-03-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-2012076763-A1 |
| titleOfInvention |
Combination anti-hiv vectors, targeting vectors, and methods of use |
| abstract |
Recombinant lentiviral vectors containing at least: a lentiviral backbone comprising essential lentiviral sequences for integration into a target cell genome; a nucleic acid encoding a CCR5 RNAi; and an expression control element that regulates expression of the nucleic acid encoding the CCR5 RNAi element, are provided by this invention. In an alternative aspect, the vector also contains polynucleotides encoding TRIMS alpha and HIV TAR decoy sequences along with gene expression regulation elements such as promoters operatively linked to the polynucleotides. The vectors are combined with packaging plasmid and envelope plasmids and optionally conjugated to cell-specific targeting antibodies. Diagnostic and therapeutic methods for using the compositions are further provided herein. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2882460-A4
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2014026053-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9663564-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9309535-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2014144815-A2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-109554447-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11339396-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2014144815-A3
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10913957-B2 |
| priorityDate |
2009-04-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |